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SERTRALINE (Zoloft®) is an antidepressant. It helps to improve a depressed person's mood. Sertraline (Zoloft®) can also help people with an obsessive compulsive disorder, panic attacks, post-trauma stress, or social anxiety. Sertraline (Zoloft®) may also be prescribed for other purposes, like premenstrual dysphoric disorder (PMDD), a severe type of premenstrual syndrome. Generic sertraline (Zoloft®) tablets are not yet available.
What should my health care professional know before I take sertraline (Zoloft®)?
They need to know if you have any of these conditions:
•bipolar disorder or a family history of bipolar disorder
•diabetes
•heart disease
•liver disease
•receiving electroconvulsive therapy
•seizures (convulsions)
•suicidal thoughts, plans, or attempt; a previous suicide attempt by you or a family member
•an unusual or allergic reaction to sertraline (Zoloft®), other medicines, foods, dyes, or preservatives
•pregnant or trying to get pregnant
•breast-feeding
How should I take this medicine (Zoloft®)?
Take sertraline (Zoloft®) tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. You may take sertraline (Zoloft®) with or without food. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.
Do not use this medication in children unless you have been specifically instructed to do so by your health care provider. Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed. A Medication Guide About Using Antidepressants in Children and Teenagers is available from your health care professional and should be read and discussed with the health care provider if this drug is being used in a child or adolescent.
What if I miss a dose (Zoloft®)?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take double or extra doses.
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What
drug(s) may interact with sertraline (Zoloft®)?
Sertraline has the potential to interact with a variety of medications, check
with your healthcare professional. The following list contains some of these
interactions.
Do not take sertraline with any of the following medications:
•astemizole (Hismanal®)
•cisapride (Propulsid®)
•pimozide (Orap®)
•terfenadine (Seldane®)
•thioridazine (Mellaril®)
•medicines called MAO inhibitors-phenelzine (Nardil®),
tranylcypromine (Parnate®), isocarboxazid (Marplan®),
selegiline (Eldepryl®)
Sertraline may also interact with the following medications:
•amphetamine
•bosentan
•carbamazepine
•certain diet drugs (dexfenfluramine, fenfluramine, phentermine, sibutramine)
•certain migraine headache medicines (almotriptan, eletriptan, frovatriptan,
naratriptan, rizatriptan, sumatriptan, zolmitriptan)
•cimetidine
•cyclosporine
•dextroamphetamine
•dextromethorphan
•diazepam
•doxercalciferol
•furazolidone
•linezolid
•other medicines for mental depression, mania, anxiety, psychosis or difficulty
sleeping
•phenobarbital
•prescription pain medications
•procarbazine
•rifabutin
•rifampin
•rifapentine
•selegiline
•St. John's wort
•tolbutamide
•tramadol
•warfarin
Tell your doctor or health care professional about all other medicines you are
taking, including non-prescription medicines, nutritional supplements, and
herbal products. Also tell your doctor or health care professional if you are a
frequent user of drinks with caffeine or alcohol, if you smoke, or if you use
illegal drugs. These may affect the way your medicine works. Check with your
health care professional before stopping or starting any of your medicines.
What
side effects may I notice from taking sertraline
(Zoloft®)?
Side effects that you should report to your doctor or health care professional
as soon as possible:
•anxiety, agitation, panic attacks, inability to sleep, irritability, hostility
or extreme anger, aggressiveness, engaging in unusual or dangerous activities,
restlessness or inability to sit still, fast talking, actions that are out of
control, extreme elation or feeling of happiness that may switch back and forth
with a depressed or sad mood
•fast heart rate, palpitations
•dizziness or lightheadedness
•skin rash, itching (hives)
•unusual tiredness or weakness
•vomiting
Side effects that usually do not require medical attention (report to your
doctor or health care professional if they continue or are bothersome):
•agitation or restlessness
•blurred vision
•constipation (less common) or diarrhea (more common)
•difficulty sleeping
•drowsiness
•dry mouth
•flushing (redness of skin)
•headache
•indigestion, nausea
•increased or decreased appetite
•increased sweating
•intestinal gas
•sexual difficulties (decreased sexual ability or desire)
•tremor (shaking)
What should
I watch for while taking sertraline (Zoloft®)?
Visit your doctor or health care professional for regular checks on your
progress. Continue to take your medicine even if you do not immediately feel
better. It can take several weeks before you feel the full effect of sertraline
(Zoloft®) . If you notice any unusual effects, such as restlessness, worsening
of depression, agitation, difficulty sleeping, irritability, anger, acting on
dangerous impulses, or thoughts of suicide or suicidal attempts, you should call
your health care provider immediately.
If you have been taking sertraline (Zoloft®) regularly for some time, do not
suddenly stop taking it. You must gradually reduce the dose or your symptoms may
get worse. Ask your doctor for advice on slowly stopping sertraline (Zoloft®).
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that
needs mental alertness until you know how sertraline (Zoloft®) affects you. Do
not stand or sit up quickly, especially if you are an older patient. This
reduces the risk of dizzy or fainting spells. Alcohol may interfere with the
effect of sertraline (Zoloft®). Avoid alcoholic drinks. Do not treat
yourself for coughs, colds or allergies without asking your doctor or health
care professional for advice. Some ingredients can increase possible side
effects.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and
drinking plenty of water will help. If you are going to have surgery, tell
your doctor or health care professional that you are taking sertraline
(Zoloft®).
Where
can I keep my Zoloft?
Keep out of the reach of children in a container that small children cannot
open. Store at room temperature between 15 and 30 degrees C (59 and 86
degrees F). Throw away any unused medicine after the expiration date.
Last Updated:08/31/2005
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