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Orlistat (Xenical®) is used to help obese people lose weight and keep the weight off while eating a reduced-calorie diet. Orlistat (Xenical®) decreases the amount of fat that is absorbed from your diet. Generic orlistat (Xenical®) capsules are not yet available.
What should my health professional know before I take Orlistat (Xenical®)?
They need to know if you have any of these conditions:
•an eating disorder, such as anorexia or bulimia
•problems absorbing food (chronic malabsorption)
•gallbladder problems or gallstones
•diabetes
•if you are taking any other weight-loss medications
•an unusual or allergic reaction to orlistat (Xenical®), other medicines, foods, dyes, supplements or preservatives
•pregnant or trying to get pregnant
•breast-feeding
How should I take this medicine (Xenical®)?
Orlistat (Xenical®) is taken by mouth and swallowed with a drink of liquid. Follow the directions on the prescription label. You can take orlistat (Xenical®) with each main meal that contains about 30% of the calories from fat. Or you can take the capsule one hour after the meal. Do not take your medicine more often than directed. If you occasionally miss a meal or have a meal without fat, you can omit that dose of orlistat (Xenical®). Doses greater than 120 mg three times per day have not been shown to increase weight loss.
You should use orlistat (Xenical®) with a reduced-calorie diet that contains no more than about 30% of the calories from fat. Divide your daily intake of fat, carbohydrates, and protein evenly over your 3 main meals. You should try to follow a healthy eating plan as prescribed by your doctor such as the one developed by the American Heart Association. Following this eating plan can help reduce the possible GI side effects from orlistat (Xenical®). Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
What
if I miss a dose (Xenical®)?
If you miss a dose, take it within one hour following the meal that contains
fat. If it is almost time for your next dose, take only that dose. Do not take
double or extra doses.
What
drug(s) may interact with Orlistat (Xenical®)?
•Dietary supplements, such as beta-carotene and vitamins A, D, E, and K
•warfarin
•cyclosporine
•pravastatin
•drugs used to treat diabetes
Since orlistat can cause decreased absorption of some fat-soluble vitamins, you
may need to take a daily multivitamin that contains normal amounts of vitamins
D, E, K and beta-carotene. Take the multivitamin once per day at least 2 hours
after your dose of orlistat (Xenical®) unless otherwise directed by your
physician or other healthcare professional.
Tell your doctor or other health care professional about all other medicines you
are taking including non-prescription medicines, nutritional supplements, or
herbal products. Also, tell your doctor or health care professional if you are a
frequent user of drinks with caffeine or alcohol, if you smoke or if you use
illegal drugs. These may affect the way your medicine works. Check before
stopping or starting any of your medications.
What
side effects may I notice from taking Orlistat (Xenical®)?
The side effects seen with orlistat (Xenical®) are related to the reduced
absorption of fat from your diet. Gastrointestinal (GI) side effects may last
for less than one week, but have occurred for up to 6 months or longer.
Maintaining an appropriate diet can help decrease side effects. The use of
orlistat (Xenical®) for greater than 2 years has not been studied.
Side effects that you should report to your doctor or health care professional
as soon as possible:
•arthritis or joint pain/tenderness
•back pain
•rash, itching, or shortness of breath
•severe stomach pain
•yellow color appearing in your skin or the whites of your eyes
•weakness or fainting
Side effects that usually do not require medical attention (report to your
doctor or health care professional if they continue or are bothersome):
•stomach discomfort
•increased number of bowel movements
•loss of control of bowel movements
•urgent need to go to the bathroom
•gas with release of stool
•oily/fatty stools
•oily discharge
•clear, orange or brown colored bowel movements
What should
I watch for while taking Orlistat (Xenical®)?
Watch for any unusual changes in your body's normal function. You need to watch
the amount of fat in your diet. Too much dietary fat can increase the side
effects from orlistat (Xenical®). Also, watch for any changes in your eyesight,
skin or hair that may be caused by a vitamin deficiency.
Where
can I keep my medicine (Xenical®)?
Keep out of the reach of children in a container that small children cannot
open.
Storage at 25[0] C (77[0] F) is preferred. You may store at 15[0] to 30[0] C
(59[0] to 86[0] F). Protect from moisture. Keep container tightly closed. Throw
away any unused medicine after the expiration date.
Last Updated:09/15/2005
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XENICAL i
s available as a dark-blue, hard-gelatin capsule, with light-blue imprinting. Each capsule contains 120 mg of the active ingredient orlistat.HOW DOES XENICAL WORK?
XENICAL does not act centrally on the brain to reduce appetite. Its action takes place in the lumen of the stomach and absorption of the drug into the blood is minimal. In contradistinction, most other weight loss medicines act on specific areas of the brain to reduce appetite. You eat less, you lose weight - but at a price. In order to get to the brain, these drugs must enter the blood stream. Therefore, these drugs may have systemic side effects (central nervous system and cardiovascular), ranging from minor to severe and are indicated only for short-term use. But, most important, these drugs do little if anything to help people change their eating habits or lifestyles. Therefore, when they stop taking the drugs, the weight is quickly regained.
XENICAL, on the other hand, is a reversible inhibitor of lipases made in the stomach and pancreas. Lipases are enzymes that break down fat. After we eat a fatty meal (such as meat) fats reach the stomach in a form called triglycerides. Triglycerides cannot be absorbed into the blood unless lipases break them down into compounds called fatty acids. XENICAL prevents this breakdown and the undigested triglycerides are excreted into the stool. The resulting decrease in caloric intake can have a positive effect on weight control.
HOW MUCH WEIGHT CAN I LOSE WITH XENICAL?
There is no clear-cut amount of weight that can be lost when taking XENICAL. Remember, in order for XENICAL to work optimally you must restrict your fat intake and increase exercise. If you are committed to your weight loss program there is essentially no limit as to how much weight you can loose. Nonetheless, weight loss should be gradual and always be done safely. While it is important that you decrease you fat intake it is equally as important that you eat healthy and insure you obtain all essential nutrients each and every day. Keep in mind that even a small amount of weight loss can reward you with a big gain in your health. A loss of 5 to 10% of your current weight can result in a significant reduction of risk for disease.
CLINICAL EFFICACY STUDIES :
Pooled data from multiple trials indicated that weight loss averaged 12.4 lbs. to 13.4 lbs. in patients taking XENICAL. Overall 57% of treated patients lost over 5% of their base-line body weight. Those on XENICAL showed a decrease in total blood cholesterol and LDL cholesterol (low density cholesterol). This form of cholesterol acts to promote the deposition of fatty plaques along the walls of arteries. There was a concomitant increase in HDL cholesterol (high density cholesterol). This form of cholesterol acts to inhibit the deposition of fatty plaques along the walls of arteries. In international clinical studies with thousands of patients, most individuals using XENICAL lost, on average, 10% of their initial body weight over a 6-8 month period.
ARE THERE OTHER BENEFITS TO TAKING XENICAL?
In addition to reducing weight, XENICAL reduces :
- high blood pressure.
- the amount of anti-diabetic medication required (if already diabetic).
- triglycerides.
- body fat.
- the chance of developing type II diabetes.
WHO SHOULD TAKE XENICAL?
XENICAL is a serious weight loss medication, indicated only for those who are truly obese (obesity is defined as having an initial body mass index greater than or equal to 30 kg/m2 or 27 kg/m2 in the presence of other risk factors such as hypertension, diabetes or increased serum cholesterol). The initial body mass index is calculated utilizing the patient’s height and weight. Therefore it in not generally recommended that it be used as a “summer” medication for transient weight loss. It is most commonly recommended that it be prescribed for those who are willing to make serious permanent changes in their eating and exercise habits
WHEN SHOULD I START TAKING XENICAL?
When you are ready to control your diet so that no more than one third of calories come from fat and you are willing to commit yourself to beginning and continuing with a graded exercise program you are then ready to start taking XENICAL.
HOW DO I START TAKING XENICAL?
Questions that should be answered before I begin this medicine include :
- Am I overweight?
- Am I at risk for diseases associated with being overweight?
- How much weight can I realistically lose?
- Can I achieve this goal with diet and exercise alone?
- Am I committed to managing my weight?
- What kinds of support will I require to help me manage my weight (such as
nutritionist, dietician, physical therapist, or psychologist)?
- Are these resources available to me?
WHAT IS THE CORRECT DOSAGE OF XENICAL?
One capsule (120milligrams) is taken three times daily with each main meal - up two hours after eating. Taking a capsule with each meal is convenient and easy to remember.
HOW QUICKLY DOES XENICAL WORK?
In one clinical study, weight loss attributed to XENICAL was seen as early as 2 weeks after starting this medicine. In patients who participate in a graded exercise program that slowly increases the amount of physical activity performed each week, weight loss my be seen ever faster.
HOW LONG CAN I CONTINUE TAKING XENICAL?
One of the benefits of XENICAL is that while you lose weight, you are changing your eating habits and lifestyle. By the time you have reached your goal, you may be able to maintain your weight through diet and exercise alone. If, however, you start to regain weight, you can safely resume taking XENICAL. XENICAL has been shown to be safe for up to two years of continuous use. XENICAL can become part of your long-term weight maintenance program.
DO I HAVE TO TAKE VITAMIN SUPPLEMENTS?
Yes, it is worthwhile to take a vitamin supplement that contains fat-soluble
vitamins such as vitamin A and D. XENICAL has been shown to reduce the
absorption of some fat-soluble vitamins and beta-carotene. The supplement should
be taken once a day at least 2 hours before or 2 hours after a dose of
XENICAL. Bedtime is a very convenient time to take your vitamin.
IF I TAKE MORE THAN ONE CAPSULE AT A TIME, WILL IT BLOCK MORE FAT?
No. There is absolutely no benefit to taking more than the recommended dose.
DO I HAVE TO TAKE A CAPSULE WITH EVERY MEAL?
If you skip a meal or your meal contains little fat (note: be careful of the hidden fats in many foods), there is no reason to take XENICAL, although there is no harm in taking the capsule. Taking a capsule with each meal will help you to remember and avoid missing doses.
WHAT IF I EAT MORE THAN THREE MEALS A DAY?
It is strongly recommended that you eat several meals throughout the day. But, you should not take more than 3 XENICAL capsules per day.
WHAT IF I MISS TAKING A CAPSULE WITH A MEAL?
Nothing. You simply miss the benefit of the medication.
DOES XENICAL INTERACT WITH OTHER MEDICATIONS?
Clinical studies have shown that XENICAL does not interact with commonly used medications. However, before starting XENICAL it is essential that you tell us on your medical history/personal profile of any and all medications (prescription and non-prescription) that you are currently taking.
DOES XENICAL HAVE ANY SIDE EFFECTS?
XENICAL has none of the side effects normally associated with diet
medications that act on the brain. XENICAL’s side effects are strictly
gastrointestinal in nature and related to its action of blocking the digestion
of ingested fat. The fat that is not absorbed into the bloodstream remains in
the intestine and becomes mixed with the stool. The increased fat in the stool
can cause any of the following :
- gas (flatulence) - sometimes with oily
spotting
- increased frequency of bowel movements
- fatty/ oily stool
How often or how quickly these effects occur will vary from person to person and will depend on how much extra fat was consumed. They can occur within hours after eating a meal or up to a day or two later. These side effects usually occur early in treatment, last for only a short period, and disappear over time. Importantly, you can control the effects if you control your fat intake. Remember: it's not the XENICAL, it's the fat you eat that causes the events.
COULD I BECOME ADDICTED TO XENICAL?
Physiological dependence does not occur because XENICAL is not absorbed into the blood. Nonetheless, psychological dependence can rarely become a problem. Thus, the notion that this medicine is totally non-addictive is false.
CAN I OVERDOSE ON XENICAL?
XENICAL is very safe. There have been no cases of overdosing. In experiments, patients who took doses of XENICAL many times over the recommended dose experienced no ill effects. Remember, taking more XENICAL gives no extra benefit.
Xenical is available as a dark-blue, hard-gelatin capsule, with light-blue imprinting. Each capsule contains 120 mg of the active ingredient orlistat .
Xenical does not act centrally on the brain to reduce appetite. Xenical 's action takes place in the lumen of the stomach and absorption of Xenical into the blood is minimal. In contradistinction, most other weight loss medicines act on specific areas of the brain to reduce appetite. You eat less, you lose weight - but at a price. In order to get to the brain, these drugs must enter the blood stream. Therefore, these drugs may have systemic side effects (central nervous system and cardiovascular), ranging from minor to severe and are indicated only for short-term use. But, most important, these drugs do little if anything to help people change their eating habits or lifestyles. Therefore, when they stop taking the drugs, the weight is quickly regained.
Xenical , on the other hand, is a reversible inhibitor of lipases made in the stomach and pancreas. Lipases are enzymes that break down fat. After we eat a fatty meal (such as meat) fats reach the stomach in a form called triglycerides. Triglycerides cannot be absorbed into the blood unless lipases break them down into compounds called fatty acids. Xenical prevents this breakdown and the undigested triglycerides are excreted into the stool. The resulting decrease in caloric intake can have a positive effect on weight control.
HOW MUCH WEIGHT CAN I LOSE WITH XENICAL?
There is no clear-cut amount of weight that can be lost when taking Xenical . Remember, in order for Xenical to work optimally you must restrict your fat intake and exercise. If you are committed to your weight loss program there is essentially no limit as to how much weight you can loose with Xenical . Nonetheless, weight loss should be gradual and always be done safely. While it is important that you decrease you fat intake while using Xenical it is equally as important that you eat healthy and insure you obtain all essential nutrients each and every day. Keep in mind that even a small amount of weight loss can reward you with a big gain in your health. A loss of 5 to 10% of your current weight can result in a significant reduction of risk for heart disease.
CLINICAL EFFICACY STUDIES OF XENICAL :Pooled data from multiple trials with Xenical indicated that weight loss averaged 12.4 lbs. to 13.4 lbs. in patients taking Xenical . Overall 57% of treated patients lost over 5% of their base-line body weight. Those on Xenical showed a decrease in total blood cholesterol and LDL cholesterol (low density cholesterol). This form of cholesterol acts to promote the deposition of fatty plaques along the walls of arteries. There was a concomitant increase in HDL cholesterol (high density cholesterol) with Xenical . This form of cholesterol acts to inhibit the deposition of fatty plaques along the walls of arteries. In international clinical studies with thousands of patients, most individuals using Xenical lost, on average, 10% of their initial body weight over a 6-8 month period.
ARE THERE OTHER BENEFITS TO TAKING XENICAL?In addition to reducing weight:
- Xenical reduces high blood pressure.
- Xenical reduces the amount of anti-diabetic medication required (if already diabetic).
- Xenical reduces triglycerides.
- Xenical reduces body fat.
- Xenical reduces the chance of developing type II diabetes.
Xenical is a serious weight loss medication, indicated only for those who are truly obese (obesity is defined as having an initial body mass index greater than or equal to 30 kg/m2 or 27 kg/m2 in the presence of other risk factors such as hypertension, diabetes or increased serum cholesterol). The initial body mass index is calculated utilizing the patient's height and weight. Therefore it is not generally recommended that Xenical be used as a “summer” medication for transient weight loss. Xenical is most commonly recommended for those who are willing to make serious permanent changes in their eating and exercise habits
WHEN SHOULD I START TAKING XENICAL?When you are ready to control your diet so that no more than one third of calories come from fat and you are willing to commit yourself to beginning and continuing with a graded exercise program you are then ready to start taking Xenical .
HOW DO I START TAKING XENICAL?Questions that should be answered before I begin taking Xenical include:
- Am I overweight?
- Am I at risk for diseases associated with being overweight?
- How much weight can I realistically lose?
- Can I achieve this goal with diet and exercise alone?
- Am I committed to managing my weight?
- What kinds of support will I require to help me manage my weight (such as nutritionist, dietician, physical therapist, or psychologist)?
- Are these resources available to me?
One capsule (120milligrams) of Xenical is taken three times daily with each main meal - up two hours after eating. Taking a Xenical capsule with each meal is convenient and easy to remember.
HOW QUICKLY DOES XENICAL WORK?In one clinical study, weight loss attributed to Xenical was seen as early as 2 weeks after starting this medicine. In patients who participate in a graded exercise program that slowly increases the amount of physical activity performed each week, weight loss may be seen ever faster.
HOW LONG CAN I CONTINUE TAKING XENICAL?One of the benefits of Xenical is that while you lose weight, you are changing your eating habits and lifestyle. By the time you have reached your goal, you may be able to maintain your weight through diet and exercise alone. If, however, you start to regain weight, you can safely resume taking Xenical . Xenical has been shown to be safe for up to two years of continuous use. Xenical can become part of your long-term weight maintenance program.
DO I HAVE TO TAKE VITAMIN SUPPLEMENTS?Yes, it is worthwhile to take a vitamin supplement that contains fat-soluble vitamins such as vitamin A and D. Xenical has been shown to reduce the absorption of some fat-soluble vitamins and beta-carotene. The supplement should be taken once a day at least 2 hours before or 2 hours after a dose of Xenical . Bedtime is a very convenient time to take your vitamin.
IF I TAKE MORE THAN ONE XENICAL CAPSULE AT A TIME, WILL IT BLOCK MORE FAT?No. There is absolutely no benefit to taking more than the recommended dose of Xenical .
DO I HAVE TO TAKE A XENICAL CAPSULE WITH EVERY MEAL?If you skip a meal or your meal contains little fat (note: be careful of the hidden fats in many foods), there is no reason to take Xenical , although there is no harm in taking the capsule. Taking a Xenical capsule with each meal will help you to remember and avoid missing doses.
WHAT IF I EAT MORE THAN THREE MEALS A DAY?
It is strongly recommended that you eat several meals throughout the day. But, you should not take more than 3 Xenical capsules per day.
WHAT IF I MISS TAKING A XENICAL CAPSULE WITH A MEAL?Nothing. You simply miss the benefit of Xenical .
DOES XENICAL INTERACT WITH OTHER MEDICATIONS?Clinical studies have shown that Xenical does not interact with commonly used medications. However, before starting Xenical it is essential that you tell us on your medical history/personal profile of any and all medications (prescription and non-prescription) that you are currently taking.
DOES XENICAL HAVE ANY SIDE EFFECTS?Xenical has none of the side effects normally associated with diet medications that act on the brain. Xenical 's side effects are strictly gastrointestinal in nature and related to its action of blocking the digestion of ingested fat. The fat that is not absorbed into the bloodstream remains in the intestine and becomes mixed with the stool. The increased fat in the stool can cause any of the following:
- gas (flatulence) - sometimes with oily spotting,
- increased frequency of bowel movements,
- fatty/ oily stool .
How often or how quickly these effects occur with Xenical will vary from person to person and will depend on how much extra fat was consumed. They can occur within hours after eating a meal or up to a day or two later. These side effects of Xenical usually occur early in treatment, last for only a short period, and disappear over time. Importantly, you can control the effects if you control your fat intake. Remember: it's not the Xenical , it's the fat you eat that causes the events.
COULD I BECOME ADDICTED TO XENICAL?Physiological dependence does not occur because Xenical is not absorbed into the blood. Nonetheless, psychological dependence can rarely become a problem. Thus, the notion that Xenical is totally non-addictive is false.
CAN I OVERDOSE ON XENICAL?Xenical is very safe. There have been no cases of overdosing. In experiments, patients who took doses of Xenical many times over the recommended dose experienced no ill effects. Remember, taking more Xenical gives no extra benefit.
ADDITIONAL QUESTIONS :Not every question about Xenical can be addressed in this FAQ page. If any additional questions remain we suggest you contact your local physician.
Low Cost Canada Discount Price Xenical mailed to your home.
Low Cost Canada Xenical 120 mg #84 Discount Price Canada
