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What are bupropion tablets (Wellbutrin®)?
BUPROPION (Wellbutrin®) is an antidepressant, a medicine that helps to lift
mental depression. Bupropion (Wellbutrin®) acts differently from other
antidepressants and may be useful for treating patients who have had unusual or
limiting effects from other antidepressants. Occasionally bupropion (Wellbutrin®)
is prescribed for other behavioral or emotional problems. Generic bupropion (Wellbutrin®)
tablets are available.
What
should my health care professional know before I take bupropion
(Wellbutrin®)?
They need to know if you have any of these conditions:
•frequently drink alcoholic beverages
•an eating disorder, such as anorexia or bulimia
•bipolar disorder or psychosis
•heart disease, previous heart attack, or irregular heart beat
•head injury or brain tumor
•high blood pressure
•kidney disease
•liver disease
•seizures (convulsions)
•suicidal thoughts or a previous suicide attempt
•Tourette's syndrome
•use of sedatives
•weight loss
•an unusual or allergic reaction to bupropion (Wellbutrin®), other medicines,
foods, dyes, or preservatives
•breast-feeding
•pregnant or trying to become pregnant
How
should I take this medicine (Wellbutrin®)?
Take bupropion (Wellbutrin®) tablets by mouth. Follow the directions on the
prescription label. Swallow the tablets with a drink of water. It is important
to take your doses at regular intervals. Do not take your medicine more often
than directed. Do not stop taking the tablets except on your doctor's advice.
Contact your pediatrician or health care professional regarding the use of this
medicine in children. Special care may be needed
What
if I miss a dose?
If you miss a dose, take it as soon as you can. If it is less than four hours to
your next dose, take only that dose and skip the missed dose. Do not take double
or extra doses.
What
drug(s) may interact with bupropion (Wellbutrin®)?
NOTE: Do not take bupropion (Wellbutrin®) with other medicines containing
bupropion (Wellbutrin®) , like Zyban®.
Other medicines that can interact with bupropion (Wellbutrin®)
include:
•alcohol
•amphetamine
•carbamazepine
•cimetidine
•cocaine
•corticosteroids
•dextroamphetamine
•doxercalciferol
•kava kava, Piper methysticum
•levodopa or combination drugs containing levodopa
•linezolid
•medications or herbal products for weight control or appetite
•medicines for mental depression, emotional, or psychotic disturbances
•medicines for difficulty sleeping
•medicines called MAO inhibitors-phenelzine (Nardil®), tranylcypromine (Parnate®),
isocarboxazid (Marplan®), and selegiline (Eldepryl®)
•nicotine
•orphenadrine
•phenobarbital
•phenytoin
•rifampin
•ritonavir
•some medicines for heart rhythm or blood pressure
•some medicines for migraine headache (propranolol)
•some medicines for pain, such as codeine
•St. John's wort, Hypericum perforatum
•theophylline
•tramadol
•valerian, Valeriana officinalis
•valproic acid
•warfarin
Tell your doctor or health care professional about all other medicines you are
taking, including non-prescription medicines. Also, tell your doctor or health
care professional if you are a frequent user of drinks with caffeine or alcohol,
if you smoke, or if you use illegal drugs. These may affect the way your
medicine works. Check with your health care professional before stopping or
starting any of your medicines.
What
side effects may I notice from taking bupropion (Wellbutrin®)?
Side effects that you should report to your doctor or health care professional
as soon as possible:
Uncommon:
•blurred vision
•difficulty breathing or wheezing
•fast or irregular heartbeat (palpitations)
•increased blood pressure
•hallucinations
•redness, blistering, peeling or loosening of the skin, including inside the
mouth
•unusual tiredness or weakness
More common:
•agitation, anxiety, or restlessness, especially in the first week of
treatment or when doses are changed
•confusion
•seizures
•skin rash, itching, hives
•vomiting
Side effects that usually do not require medical attention (report to your
doctor or health care professional if they continue or are bothersome):
Less common:
•loss of appetite
•loss of sexual drive
•menstrual changes
More common:
•change in taste
•constipation
•difficulty sleeping
•dizziness
•dry mouth
•headache
•increased sweating
•nausea
•tremor
•weight loss
What should
I watch for while taking bupropion (Wellbutrin®)?
Visit your doctor or health care professional for regular checks on your
progress. You may have to take bupropion (Wellbutrin®) for several days before
you see the effects. If you have been taking bupropion (Wellbutrin®) for some
time, do not suddenly stop taking it. Your doctor or health care professional
may want you to gradually reduce the dose; ask for advice.
Patients and their families should watch out for worsening depression or
thoughts of suicide. Also watch out for sudden or severe changes in feelings
such as feeling anxious, agitated, panicky, irritable, hostile, aggressive,
impulsive, severely restless, overly excited and hyperactive, or not being able
to sleep. If this happens, especially at the beginning of bupropion (Wellbutrin®)
treatment or after a change in dose, call your doctor. You may get dizzy
or have blurred vision. Do not drive, use machinery, or do anything that needs
mental alertness until you know how bupropion (Wellbutrin®) affects you. Do not
stand or sit up quickly, especially if you are an older patient. This reduces
the risk of dizzy or fainting spells.
Alcohol may increase dizziness or drowsiness; avoid alcoholic drinks while
taking bupropion (Wellbutrin®). Drinking excessive alcoholic beverages, using
sleeping or anxiety medicines, or quickly stopping the use of these agents while
taking bupropion (Wellbutrin®) may increase your risk for a seizure
(convulsion). Bupropion (Wellbutrin®) can make your mouth dry. Chewing
sugarless gum, sucking hard candy and drinking plenty of water will help.
Do not treat yourself for coughs, colds, or allergies without asking your doctor
or health care professional for advice. Also do not take any herbal or
non-prescription medicines for weight loss without your doctor's advice. Some
ingredients may increase possible side effects. If you are going to have
surgery, tell your doctor or health care professional well before your scheduled
surgery that you are taking bupropion (Wellbutrin®).
Where
can I keep my medicine (Wellbutrin®)?
Keep out of the reach of children in a container that small children cannot
open. Store at room temperature between 20 and 25 degrees C (68°and
77 degrees F), away from direct sunlight and moisture. Keep tightly closed.
Throw away any unused medicine after the expiration date.
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