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NELFINAVIR (Viracept®) is an antiviral drug called a protease inhibitor. Nelfinavir (Viracept®) is used to treat human immunodeficiency virus (HIV) infection. Nelfinavir (Viracept®) may reduce the amount of HIV in the blood and increase the number of CD4 cells (T-cells) in the blood. Nelfinavir (Viracept®) is used in combination with other drugs used to treat the HIV virus. Nelfinavir (Viracept®) will not cure or prevent HIV infection or AIDS. You may still develop other infections or conditions associated with HIV. Generic nelfinavir (Viracept®) tablets are not yet available.
What should my health care professional know before I take nelfinavir (Viracept®)?
They need to know if you have any of these conditions:
•diabetes or high blood sugar
•hemophillia
•high cholesterol or lipids in your blood
•liver disease
•received other treatments for HIV or AIDS
•an unusual or allergic reaction to nelfinavir (Viracept®), other medicines, foods, dyes, or preservatives
•breast-feeding
•pregnancy or recent attempts to get pregnant
How should I take this medicine?
Take nelfinavir (Viracept®) tablets by mouth with a meal or light snack, within 1 hour before or after a meal. Follow the directions on the prescription label. Fruit or fruit juice is not enough food to take with nelfinavir (Viracept®). Appropriate foods include cheese and crackers, cookies and milk, a granola bar, a bagel or a small sandwich. Take your doses at regular intervals. If you cannot swallow the tablets, put the whole or crushed tablets in a small amount of water to dissolve or mix crushed tablets in a small amount of food. The pills will dissolve in 1—2 minutes; there may still be some small pieces, but they should be easy to swallow. Once mixed with food or water, you must eat or drink the whole amount to get the full dose. Rinse the drinking glass and drink the rinse to ensure the entire dose is consumed. Avoid mixing nelfinavir (Viracept®) with acidic foods or juices (like orange juice, apple juice, or apple sauce) because a bitter taste may occur.
To help to make sure that your anti-HIV therapy works as well as possible, be very careful to take all of your medicine exactly as prescribed. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice. Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
What if I miss a dose (Viracept®)?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What drug(s) may interact with nelfinavir (Viracept®)?
Many medicines may interact with nelfinavir (Viracept®), if you have a question concerning other medicines you may be taking, talk with your pharmacist,doctor or other health care professional.
Do not take nelfinavir with any of these medicines:
•amiodarone (Cordarone®)
•astemizole (Hismanal®)
•bepridil (Vascor®) or mibefradil (Posicor®)
•cerivastatin (Baycol®)
•cisapride (Propulsid®)
•ergotamine medicines (such as Cafergot®, Migranal®, D.H.E. 45®, and others)
•lovastatin (Mevacor®)
•midazolam (Versed®)
•pimozide (Orap®)
•quinidine (Quinaglute®, Cardioquin®, Quinidex®, and others)
•rifampin (Rimactane®, Rifadin®, Rifater®, or Rifamate®)
•simvastatin (Zocor®)
•St. John's wort or any herbal products containing St. John's wort
•terfenadine (Seldane®)
•triazolam (Halcion®)
•went yeast (Cholestin™)
Other medicines that may interact with nelfinavir(Viracept®) :
•birth control pills or hormone-type birth control
•bosentan
•calcium-channel blockers, often used for high blood pressure or chest pain (examples: amlodipine, diltiazem, felodipine, nifedipine, nimodipine, nisoldipine, verapamil)
•certain medicines for anxiety or for difficulty sleeping
•certain medicines for fungal infections
•certain medicines for high cholesterol
•certain pain medicines
•cilostazol
•cyclosporine
•disopyramide
•dofetilide
•doxercalciferol
•imatinib, STI-571
•levomethadyl
•medicines for seizures
•medicines for depression
•medicines for diabetes
•other antiviral medicines such as delavirdine, didanosine, ddI, efavirenz, indinavir, ritonavir, saquinavir
•paricalcitol
•rifabutin
•sildenafil
•sirolimus
•tacrolimus
•went yeast (Cholestin™)
Tell your doctor or health care professional about all other medicines you are taking, including nonprescription medicines, nutritional supplements, or herbal products. Also tell your doctor or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
What side effects might I notice from taking nelfinavir (Viracept®)?
Side effects that you should report to your doctor or health care professional as soon as possible:
•difficulty breathing
•severe dizziness
•severe rash with fever
•unusual tiredness or weakness
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
•diarrhea
•gas
•headache
•nausea, vomiting
•stomach pain
•tiredness or weakness
What should I watch for while taking nelfinavir (Viracept®)?
Visit your doctor or health care professional for regular checks on your progress. Discuss any new symptoms with your doctor or health care professional.
Nelfinavir (Viracept®) will not cure HIV and you can still get other illnesses or complications associated with your disease. Taking nelfinavir (Viracept®) does not reduce the risk of passing HIV infection to others through sexual or blood contact. It is best to avoid sexual contact so that you do not spread the disease to others. For any sexual contact, use a condom. Be careful about cuts, abrasions and other possible sources of blood contact. Never share a needle or syringe with anyone. If you are a women of childbearing age and are using hormone contraceptives, then you should use another form of birth control while taking nelfinavir (Viracept®). Nelfinavir (Viracept®) may decrease the effectiveness of hormone birth control agents, including birth control pills and injections.
Where can I keep my medicine (Viracept®)?
Keep out of the reach of children in a container that small children cannot open. Store at room temperature between 15—30 degrees C (59—86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.
Last Updated:08/31/2005
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