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SALMETEROL (Serevent®) is a slow-acting bronchodilator, a medicine that opens up air passages and makes breathing easier. Salmeterol (Serevent®) is for regular use to help prevent asthma attacks or to treat the symptoms of chronic lung disease like emphysema or chronic bronchitis. It is not for use in an acute asthma attack. It can also be used to prevent exercise-induced bronchospasm, at least 30 to 60 minutes before exercise is started. You must have a quick-acting bronchodilator (such as albuterol) readily available for use in an asthma attack. A generic salmeterol inhalation aerosol (Serevent®) is not available. NOTE: This inhalation aerosol has been discontinued in the US.
What should my health care professional know before I use salmeterol (Serevent®)?
They need to know if you have any of the following conditions:
•diabetes
•heart disease, or irregular heartbeat
•high blood pressure
•over active thyroid
•pheochromocytoma
•seizures (convulsions)
•an unusual or allergic reaction to salmeterol, other medicines, foods, dyes, or preservatives
•pregnant or trying to get pregnant
•breast-feeding
How should I use this medicine?
Salmeterol (Serevent®) aerosol is for regular inhalation through the mouth. Follow the directions on the prescription label. Shake the canister well. Tilt your head back slightly. Breathe out fully, emptying as much air as possible from your lungs. Keep the inhaler about 1 inch from your open mouth (or place the mouthpiece loosely between your open lips and over your tongue), keeping the canister upright. Press down on the inhaler (one puff) while breathing in deeply and slowly. Hold your breath for at least 10 seconds and then exhale (breathe out). Wait for at least 1 to 2 minutes between puffs. Do not use more than two puffs at a time, unless your doctor or health care professional tells you otherwise. Use your inhaler at regular intervals, unless you are using it to prevent exercise-induced bronchospasm. Do not use more often than directed. Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
What if I miss a dose?
If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.
What drug(s) may interact with
salmeterol (Serevent®)?
•arsenic trioxide
•astemizole
•bepridil
•beta-blockers, often used for high blood pressure or heart problems
•caffeine
•certain antibiotics (such as clarithromycin, erythromycin, gatifloxacin,
gemifloxacin, grepafloxacin, levofloxacin, linezolid, moxifloxacin, sparfloxacin)
•chloroquine
•cisapride
•droperidol
•halofantrine
•levomethadyl
•medicines for colds and breathing difficulties
•medicines for heart disease or high blood pressure
•medicines known as MAO inhibitors, such as phenelzine (Nardil®),
tranylcypromine (Parnate®), isocarboxazid (Marplan®), and selegiline (Carbex®,
Eldepryl®)
•medicines to control heart rhythm (examples: amiodarone, disopyramide,
dofetilide, flecainide, procainamide, quinidine, sotalol)
•medicines for treating depression or mental illness (amoxapine, haloperidol,
maprotiline, pimozide, phenothiazines, risperidone, sertindole, tricyclic
antidepressants, ziprasidone)
•methadone
•pentamidine
•probucol
•some medicines for weight loss (including some herbal products, ephedra,
ephedrine, dextroamphetamine)
•steroid hormones such as dexamethasone, cortisone, hydrocortisone
•terfenadine
•theophylline
•thyroid hormones
•water pills or diuretics
Tell your doctor or health care professional about all other medicines you are
taking, including non-prescription medicines, nutritional supplements, or herbal
products. Also tell your doctor or health care professional if you are a
frequent user of drinks with caffeine or alcohol, if you smoke, or if you use
illegal drugs. These may affect the way your medicine works. Check before
starting or stopping any of your medicines.
What side effects may I notice
from using salmeterol (Serevent®)?
Side effects that you should report to your doctor or health care professional
as soon as possible:
•difficulty breathing, wheezing
•dizziness, giddiness
•fast heartbeat, palpitations, chest pain
•skin rash, hives
•swelling of the face
Side effects that usually do not require medical attention (report to your
doctor or health care professional if they continue or are bothersome):
•cough
•diarrhea
•headache
•muscle cramps and pains
•nausea, vomiting
•nervousness
•sore throat
•stomach ache
•stuffy nose
•tiredness
What should I watch for while taking
salmeterol (Serevent®)?
Check with your doctor or health care professional if your symptoms do not
improve with salmeterol (Serevent®) inhalation, or if they get worse. You may
need a change of therapy. Make sure you are using your inhaler properly. Do not
use extra or more frequent inhalations; they will not improve your condition.
NEVER use salmeterol (Serevent®) for an asthma attack, because it will take
about 30 minutes to work.
Keep a record of the number of inhalations you use so that you will know when
the canister is nearly empty. Do not float the salmeterol (Serevent®) canister
in water to test its fullness. To stop your mouth getting dry after
inhaling salmeterol (Serevent®), rinse out your mouth with water.
Do not get the aerosol spray in your eyes.
Do not treat yourself for coughs, colds or allergies without checking with your
pharmacist or doctor or health care professional. Non-prescription medicines may
contain ingredients that will increase the effects of your medicine.
If you are going to have surgery tell your doctor or health care professional
that you are using salmeterol (Serevent®).
About once a week, remove the metal canister and clean the inhaler with soap and
water, rinsing well with warm running water. Allow to dry completely before
replacing the metal canister.
Where can I keep my medicine
(Serevent®)?
Keep out of the reach of children. Store at room temperature below 30
degrees C (86 degrees F); do not freeze. Protect from light. Throw away any
unused medicine after the expiration date.
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