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What are lamotrigine tablets or chewable (Lamictal®)
tablets?
LAMOTRIGINE (Lamictal®) is effective in helping to control partial seizures
(convulsions) in adults and children with epilepsy. Lamotrigine (Lamictal®) is
also used in adults and children who have generalized (major) seizures
(convulsions) due to a special condition named Lennox-Gastaut syndrome.
Lamotrigine (Lamictal®) is usually prescribed with other medications that also
help to control the convulsions, although sometimes lamotrigine (Lamictal®) may
be used by itself. Generic lamotrigine (Lamictal®) tablets are not yet
available.
What
should my health care professional know before I take lamotrigine
(Lamictal®)?
They need to know if you have any of these conditions:
•folate deficiency
•kidney disease
•liver disease
•an unusual or allergic reaction (including rash) to lamotrigine (Lamictal®),
other medicines, foods, dyes, or preservatives
•pregnant or trying to get pregnant
•breast-feeding
How
should I take this medicine?
•If you take regular Lamictal® tablets: Take lamotrigine (Lamictal®)
tablets by mouth. Follow the directions on the prescription label. Swallow the
tablets with a drink of water. Do not chew these tablets--they have a bitter
taste. If lamotrigine (Lamictal®) upsets your stomach, take it with food or
milk. Take your doses at regular intervals. Do not take your medicine more often
than directed.
•If you take Lamictal® Chewable Dispersible tablets: Take these
lamotrigine (Lamictal®) tablets by mouth. These tablets may be swallowed whole,
chewed, mixed in water, or in diluted fruit juice to aid swallowing. To mix the
tablets in water or juice, add the tablets to a small amount of liquid (enough
to cover the medication) in a glass or spoon. The tablets will dissolve in about
1 minute. Once dissolved, mix or swirl the liquid and take the entire solution
immediately. It is important that you swallow all of the liquid used to prepare
the dose, so that the full prescribed dose is given. Take your doses at regular
intervals. Do not take your medicine more often than directed. Contact
your pediatrician or health care professional regarding the use of this
medication in children. Special care may be needed.
What
if I miss a dose (Lamictal®)?
If you miss a dose, take it as soon as you can. If it is almost time for your
next dose, take only that dose. Do not take double or extra doses.
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What
drug(s) may interact with lamotrigine (Lamictal®)?
•acetaminophen (e.g., Tylenol®)
•bosentan
•carbamazepine
•medicines used to treat HIV or AIDS infection (examples: indinavir, ritonavir)
•methotrexate
•phenobarbital
•phenytoin
•primidone
•pyrimethamine
•rifampin
•sevelamer
•trimethoprim
•valproic acid
Tell your doctor or health care professional about all other medicines you are
taking, including non-prescription medicines, nutritional supplements, or herbal
products. Also tell your doctor or health care professional if you are a
frequent user of drinks with caffeine or alcohol, if you smoke, or if you use
illegal drugs. These may affect the way your medicine works. Check with your
health care professional before stopping or starting any of your medicines.
What
side effects may I notice from taking lamotrigine (Lamictal®)?
Most people who take lamotrigine (Lamictal®) tolerate it well. The most common
side effects are dizziness, drowsiness, headache, blurred vision, nausea, and
rash. If a skin rash occurs at any time while taking lamotrigine (Lamictal®),
contact your doctor immediately. Rashes may be very severe and sometimes
requires being treatment in the hospital. Deaths from rashes have occurred.
Serious rashes occur more often in children than adults taking lamotrigine (Lamictal®).
It is more common for these serious rashes to occur during the first 2 months of
treatment, but a rash can occur at any time.
Side effects that you should report to your doctor or health care professional
immediately:
•fever
•painful sores in the mouth, eyes, or nose
•redness, blistering, peeling or loosening of the skin, including inside the
mouth
•skin rash of any type, itching
•swelling of the face, lips or tongue
•swollen lymph glands
Side effects you should report to your doctor or health care professional as
soon as possible:
•blurred, or double vision
•changes in seizure type or frequency
•depression, or mood changes
•difficulty walking or controlling muscle movements
•uncontrollable eye movements
•unusual weakness or tiredness
Side effects that usually do not require medical attention (report to your
doctor or health care professional if they continue or are bothersome):
•back pain, joint aches and pains
•diarrhea, or constipation
•difficulty sleeping
•dizziness, drowsiness
•dry mouth
•headache
•hot flashes
•loss of appetite
•menstrual disorder
•nausea, vomiting
•slurred speech
•stomach upset, indigestion
•stuffy, runny nose
•tremor
What should
I watch for while taking lamotrigine (Lamictal®)?
Visit your doctor or health care professional for a regular check on your
progress. Wear a Medic Alert bracelet or necklace. Carry an identification card
with information about your condition, medications, and doctor or health care
professional. It is important to take lamotrigine (Lamictal®) exactly as
instructed by your health care professional. When first starting lamotrigine (Lamictal®)
treatment, you doctor will have to adjust your dosage slowly, and it may take
weeks or months before your dose is stable. You should contact your doctor or
health care professional if your seizures get worse or if you have any new types
of seizures. Do not stop taking lamotrigine (Lamictal®) or any of your seizure
medicines unless instructed by your doctor or health care professional. Stopping
your medicine suddenly can increase your seizures or their severity.
You may get drowsy, dizzy (more common in women than in men), or have blurred
vision. Do not drive, use machinery, or do anything that needs mental alertness
until you know how lamotrigine (Lamictal®) affects you. To reduce dizzy or
fainting spells, do not sit or stand up quickly, especially if you are an older
patient. Alcohol can increase drowsiness and dizziness. Avoid alcoholic drinks
or medicines containing alcohol. If you are going to have surgery, tell
your doctor or health care professional that you are taking lamotrigine (Lamictal®).
Where
can I keep my medicine (Lamictal®)?
Keep out of reach of children in a container that small children cannot open.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F).
Throw away any unused medicine after the expiration date.
Last Updated:07/29/2005
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