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What are alendronate tablets (Fosamax®)?
ALENDRONATE (Fosamax®) reduces calcium loss from bones. It helps prevent bone
loss and increases production of normal healthy bone in patients with Paget's
disease, osteoporosis, and other conditions which place someone at risk for bone
loss, including after menopause in females or from the long-term use of
corticosteroids (like prednisone) in men or women. Generic alendronate (Fosamax®)
tablets are not yet available.
What
should my health care professional know before I take alendronate
(Fosamax®)?
They need to know if you have any of these conditions:
•dental disease
•kidney disease
•low level of blood calcium
•stomach, intestinal, or esophageal problems, like acid-reflux or GERD
•problems swallowing
•vitamin D deficiency
•an unusual or allergic reaction to alendronate(Fosamax®) , other medicines,
foods, dyes, or preservatives
•pregnant or trying to get pregnant
•breast-feeding
How
should I take this medicine (Fosamax®)?
Follow the directions on the prescription label. Some patients take alendronate
(Fosamax®)every day. Other patients may only take a dose of alendronate (Fosamax®)
once a week. If you take alendronate (Fosamax®) only once a week, take the
medicine on the same day every week.
Take alendronate (Fosamax®) tablets by mouth in the morning, after you have
risen for the day. Swallow the tablets with a full glass (6—8 fluid ounces) of
plain water first thing in the morning. Do not take the tablets with any other
type of liquid except plain water. Do not take with orange juice, coffee or
other fluids as these may decrease the absorption of alendronate (Fosamax®). Do
not chew or suck on the tablets; this may cause mouth ulcers (sores). Do not eat
or drink anything before you take your tablets and do not eat breakfast, drink,
or take any other medicines for at least 30 minutes after taking alendronate (Fosamax®).
If you can wait for 2 hours before eating, your body will absorb even more of
the medicine. After taking this medicine, remain sitting or standing upright (do
not lie down) for at least 30 minutes to avoid irritation of your throat and
esophagus (tube connecting mouth to stomach). Do not take this medicine at the
same time as antacids, calcium, magnesium or iron supplements, or vitamins with
minerals; if you take these medications, take them later in the day. Do not take
your medicine more often than directed. Contact your pediatrician or
health care professional regarding the use of this medicine in children. Special
care may be needed.
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What
if I miss a dose (Fosamax®)?
If you take a daily dose of alendronate (Fosamax®): If you miss a dose, do not
take it later in the day. Continue your normal schedule starting the next
morning, before you have eaten. Do not take double or extra doses. If you
take a once-weekly dose of alendronate (Fosamax®): If you miss a dose of
alendronate (Fosamax®) 35-mg or 70-mg once a week, take the dose on the morning
after you remember. Then return to taking your dose just once a week, as
originally scheduled on your regular chosen day of the week. Never take 2
tablets on the same day. Do not take double or extra doses.
What
drug(s) may interact with alendronate (Fosamax®)?
•aluminum hydroxide
•antacids
•anti-inflammatory drugs like ibuprofen, naproxen, and others
•aspirin
•calcium supplements
•iron supplements
•magnesium supplements
•parathyroid hormone
•teriparatide
•vitamins with minerals
Tell your doctor or health care professional about all other medicines you are
taking including non-prescription medicines. Also tell your doctor or health
care professional if you are a frequent user of drinks with caffeine or alcohol,
if you smoke, or if you use illegal drugs. These can affect the way your
medicine works. Check with your health care professional before stopping or
starting any of your medicines.
What
side effects might I notice from taking alendronate (Fosamax®)?
Side effects that you should report to your doctor or health care professional
as soon as possible:
More common
•stomach pain
•heartburn
•pain or difficulty swallowing
Rare or uncommon:
•allergic reactions such as skin rash or itching, hives, swelling of the
face, lips, throat or tongue
•black or tarry stools
•constant jaw pain, especially burning or cramping
•eye inflammation, pain or change in vision
•muscle twitching
•redness, blistering, peeling or loosening of the skin, including inside the
mouth
•vomiting
Side effects that usually do not require medical attention (report to your
doctor or health care professional if they continue or are bothersome):
•diarrhea or constipation
•headache
•stomach gas or fullness
•nausea
•changes in taste
•bone, muscle or joint pain
•rash, which may be made worse by prolonged exposure to sunlight
What should
I watch for while taking alendronate (Fosamax®)?
Visit your doctor or health care professional for regular checks on your
progress. If you have Paget's disease it may be some time before you see the
benefit from alendronate (Fosamax®). Do not stop taking alendronate (Fosamax®)
except on your doctor's advice. Low blood levels of phosphorus and calcium can
occur but usually do not cause serious problems. Your doctor or health care
professional may order regular blood tests to check for these problems. It
is very important to take alendronate (Fosamax®) with a full glass of water (6—8
ounces). Do not take with orange juice, coffee or other fluids as these may
decrease the absorption of alendronate (Fosamax®). Do not take alendronate (Fosamax®)with
food. Wait at least 30 minutes or longer after taking alendronate before you
eat, drink or take other medicines.
Because alendronate (Fosamax®) may irritate your throat, remain sitting or
standing upright for at least 30 minutes after taking alendronate (Fosamax®); do
not lie down. If you begin to have pain when swallowing, difficulty
swallowing, heartburn or stomach pain, call your doctor or health care
professional right away. You should make sure you get enough calcium and
vitamin D in your diet while you are taking alendronate (Fosamax®), unless
directed otherwise by your health care provider. Discuss your dietary needs with
your health care professional or nutritionist. If you get bone pain, or a
worsening of bone pain, check with your doctor. However, many patients have
improvement in their bone pain during and after treatment with alendronate (Fosamax®).
If you are taking an antacid, a mineral supplement like calcium or iron, or a
vitamin with minerals, make sure that you wait at least 30 minutes, and
preferably 2 hours before or after taking alendronate (Fosamax®). Do not take
them at same time. Limit your time in sunlight or other UV exposure, such
as tanning beds, while taking alendronate (Fosamax®). Alendronate (Fosamax®) may
cause a rash that is worsened by exposure to the sun.
Where
can I keep my (Fosamax®)?
Keep out of the reach of children in a container that small children cannot
open. Store at room temperature between 15—30 degrees C (59—86 degrees F).
Throw away any unused medicine after the expiration date.
Last Updated:02/09/2005
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