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What are
letrozole tablets (Femara®)?
LETROZOLE (Femara®) blocks the formation of the hormone estrogen. Some types of
breast cancer need estrogen, and letrozole (Femara®) stops tumor growth by
decreasing estrogen levels. Letrozole (Femara®) is for the treatment of breast
cancer in postmenopausal women only. Generic letrozole (Femara®) tablets are not
yet available.
What should my
health care professional know before I take letrozole (Femara®)?
They need to know if you have any of these conditions:
•liver disease
•osteoporosis
•an unusual or allergic reaction to letrozole (Femara®), other medicines, foods,
dyes, or preservatives
•pregnant or trying to get pregnant
•breast-feeding
How should I take
this medicine (Femara®)?
Take letrozole tablets by mouth at the same time each day. Follow the directions
on the prescription label. Swallow the tablets with a drink of water. Do not
take your medicine more often than directed. Do not stop taking except on your
doctor's advice.
Contact your pediatrician or health care professional regarding the use of this
medicine in children. Special care may be needed.
What if I miss a
dose (Femara®)?
If you miss a dose, take it as soon as you can. If it is almost time for your
next dose, take only that dose. Do not take double or extra doses. If you vomit
after taking a dose, call your doctor or health care professional for advice.
What drug(s) may
interact with letrozole (Femara®)?
•androstenedione
•any medicine containing estrogens (This may include some herbal products and
some birth control pills)
•DHEA
Tell your doctor or health care professional about all other medicines you are
taking, including nonprescription medicines, nutritional supplements, or herbal
products. Also tell your doctor or health care professional if you are a
frequent user of drinks with caffeine or alcohol, if you smoke, or if you use
illegal drugs. These may affect the way your medicine works. Check with your
health care professional before stopping or starting any of your medicines.
What side effects
may I notice from taking letrozole (Femara®)?
Side effects that you should report to your doctor or health care professional
as soon as possible:
•difficulty breathing
•chest pain
•leg pain or swelling
•skin rash
Side effects that usually do not require medical attention (report to your
doctor or health care professional if they continue or are bothersome):
•back or bone pain
•cough, or throat infection
•diarrhea or constipation
•dizziness
•headache
•hair loss
•hot flashes
•loss of appetite
•nausea, vomiting
•stomach pain or upset stomach
•sweating
•weakness or tiredness
•weight gain
What should I watch for
while taking letrozole (Femara®)?
Visit your doctor or health care professional for regular checks on your
progress. Let your doctor or health care professional know about any unusual
vaginal bleeding.
Do not treat yourself for diarrhea, nausea, vomiting or other side effects. Ask
your doctor or health care professional for advice.
Where can I keep
my medicine (Femara®)?
Keep out of the reach of children in a container that small children cannot
open. Store between 15 and 30 degrees C (59 and 86 degrees F). Throw away
any unused medicine after the expiration date.
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