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What are amiodarone
tablets?
AMIODARONE (Cordarone®) is an antiarrhythmic agent and is used to
help your heart to beat regularly. Because this drug can have significant
side-effects, this is a medicine that is used when irregular heartbeats have not
responded to other medicines. Generic amiodarone tablets are available.
What
should my health care professional know before I take amiodarone?
They need to know if you have any of these conditions:
•other heart problems
•liver disease
•thyroid disease
•lung disease
•an unusual or allergic reaction to amiodarone, iodine, other medicines, foods,
dyes, or preservatives
•pregnant or trying to get pregnant
•breast-feeding
How
should I take this medicine?
Take amiodarone tablets by mouth. Follow the directions on the prescription
label. Swallow the tablets with a drink of water. Do not take amiodarone with
grapefruit juice, as this affects how amiodarone is absorbed and may increase
the risk of side effects. Take your doses at regular intervals. Do not take your
medicine more often than directed. Keep taking your medicine even if you feel
better; do not stop taking except on your doctor's advice.
•For all uses of this medicine:
Before starting this medication, read the paper on your prescription provided by
your pharmacist or health care professional. This paper will tell you about the
specific product you are taking. Make certain you understand the instructions.
Ask your pharmacist or health care provider if you have questions.
Contact your pediatrician or health care professional regarding the use of this
medicine in children. Special care may be needed.
What
if I miss a dose?
If you miss a dose, only take it if you remember within an hour, otherwise wait
until your next dose is due. Do not take double or extra doses.
What
drug(s) may interact with amiodarone?
•arsenic trioxide
•astemizole
•beta-blockers or calcium-channel blockers, often used for high blood pressure
or heart problems
•bosentan
•certain antibiotics (such as clarithromycin, erythromycin, gatifloxacin,
gemifloxacin, grepafloxacin, levofloxacin, moxifloxacin, sparfloxacin,
troleandomycin)
•cevimeline
•cholestyramine
•cimetidine
•cisapride
•cyclosporine
•dextromethorphan
•dolasetron
•doxercalciferol
•fentanyl
•grapefruit juice
•ginger
•halofantrine
•hawthorn
•medicines for angina, high blood pressure, or heart failure
•medicines for colds or breathing difficulties (including asthma)
•medicines for HIV infection
•medicines for mental depression such as tricyclic antidepressants
•medicines for mental problems or psychotic disturbances
•medicines for seizures (convulsions) such as phenytoin
•medicines for thyroid problems
•medicines to control heart rhythm (examples: digoxin, disopyramide, dofetilide,
sotalol, procainamide, quinidine)
•medicines to lower cholesterol such as atorvastatin, cerivastatin, lovastatin,
or simvastatin
•radiopaque contrast agents
•rifampin, rifabutin, or rifapentine
•pimozide
•probucol
•pyridoxine or vitamin B6
•ramelteon
•sevelamer
•sirolimus or tacrolimus
•St. John's Wort
•terfenadine
•tramadol
•voriconazole
•warfarin
•water pills (diuretics)
•went yeast (example: Cholestin®)
Tell your doctor or health care professional about all other medicines you are
taking, including non-prescription medicines, nutritional supplements, or herbal
products. Also tell your doctor or health care professional if you are a
frequent user of drinks with caffeine or alcohol, if you smoke, or if you use
illegal drugs. These may affect the way your medicine works. Check with your
health care professional before stopping or starting any of your medicines.
What
side effects may I notice from taking amiodarone?
Side effects that you should report to your doctor or health care professional
as soon as possible:
•appetite increase or decrease
•blue-gray coloring of the skin
•blurred vision, seeing blue-green halos, increased sensitivity of the eyes to
light
•chest pain
•cough, or difficulty breathing
•difficulty walking
•dry or puffy skin or eyes
•feeling faint or light-headed
•heart pounding or skipping a beat
•heart beating very fast or very slow
•intolerance to heat or cold
•nervousness
•numbness or tingling in hands or feet
•pain and swelling of the scrotum
•passing brown or dark-colored urine
•skin rash
•sleep difficulties
•spitting up blood
•sweating
•trembling or shaking hands
•unusual or uncontrolled movements of body
•unusual tiredness or weakness
•vomiting
•weight gain or loss
•yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your
doctor or health care professional if they continue or are bothersome):
•bitter or metallic taste in the mouth
•constipation
•decreased sexual ability or desire in men
•dizziness
•flushing of the face
•headache
•nausea
What should
I watch for while taking amiodarone?
Visit your doctor or health care professional for regular checks on your
progress. Check with your doctor or health care professional if you develop a
cough or have any difficulty breathing. Because your condition and use of this
medicine carry some risk, it is a good idea to carry an identification card,
necklace or bracelet with details of your condition, medications, and doctor or
health care professional.
Amiodarone can cause serious side effects including significant lung damage,
liver damage, vision changes, thyroid dysfunction, skin problems, and worse
heartbeat problems. It is very important to have regular checks with your health
care professional. Notify your doctor immediately if you notice symptoms that
are listed in the side effects section, or any other persistent problems or
unusual reactions.
Amiodarone can make your skin more sensitive to the sun. Keep out of the sun, or
wear protective clothing outdoors and use a sunscreen. Do not use sun lamps or
sun tanning beds or booths. Your eyes may get dry while you are using
amiodarone. Use artificial tears (eye-drops containing methylcellulose) and
check with your doctor or health care professional for regular eye examinations.
If you are going to have surgery tell your doctor or health care professional
that you are taking amiodarone.
Where
can I keep my Amiodarone?
Keep out of the reach of children in a container that small children cannot
open. Store at room temperature, approximately 25 degrees C (77 degrees
F). Protect from light. Keep container tightly closed. Throw away any unused
medicine after the expiration date.
For more information see DrugDigest.org
Last Updated:08/31/2005
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